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Transthoracic Echocardiography in COVID-19

Echocardiography can identify left and right ventricular dysfunction, intracardiac thrombus, high filling pressures, particularly on the right side, as indicated by a distended inferior vena cava that does not collapse with inspiration and elevated right ventricular systolic pressures.

Indications for transthoracic echocardiography in COVID-19 patients:

  • Those with moderate or severe COVID-19 disease and cardiac troponin or BNP elevation or pre-existing disease combination with high inflammatory markers
  • Hemodynamic instability, suspicion of left ventricular or right ventricular dysfunction
  • Pulmonary embolism
  • Dedicated echocardiography in significantly elevated troponin or ECG abnormalities and/or concern for congestive heart failure

Abnormalities observed in COVID-19 patients:

  • Left ventricular dysfunction (diffuse or segmental)
  • Increased wall thickness (pseudohypertrophy-myocarditis)
  • Intracardiac thrombosis
  • Pericardial effusion
  • Reduced Tricuspid annular plane systolic excursion (TAPSE) and right ventricular function
  • Elevated right ventricular systolic pressures, Inferior vena cava distension without respiratory variation (not valid for patients in ventilation)
  • Raised right ventricular filling pressures
  • Evidence of stress cardiomyopathy

Significance in COVID-19 patients:

Focused echocardiography should be performed ONLY in those where management is likely to be influenced.

  • Limited studies to address specific clinical questions
  • Left ventricular hypertrophy and left ventricular dysfunction, and pericardial effusion may indicate myocarditis
  • Combination of congestion on lung ultrasound with high right ventricular filling pressures may signal imminent cardiovascular decline; consider ICU admission/intubation

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