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ANCA and Anti-ds DNA Tests To Diagnose CVD & SLE

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ANCA

• Used in the diagnosis and management of Collagen Vascular Disease

• ANCA by IFA is highly sensitive

• c-ANCA (PR3) is increased in

  • Systemic Necrotizing Vasculitis
  • Wegener’s Granulomatosis
  • Churg Strauss Syndrome
C-ANCA

C-ANCA Pattern

• p-ANCA (MPO) is increased in

  • Connective Tissue Disease
  • Inflammatory Bowel Disease
  • Autoimmune Liver Disease
P-ANCA

P-ANCA Pattern

Anti-ds DNA

By NcX ELISA

• Essential in the diagnosis of SLE. It is also detected in patients with other autoimmune diseases

• Anti-dsDNA is significant for the prognosis of SLE & monitoring the disease activity

• Sensitivity in patients with SLE is 70%

• Specificity in patients with autoimmune diseases is 99%

 

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Book your appointment to diagnose Collagen Vascular Disease & CLE at Suburban Diagnostics.

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