Suburban blog

ANCA and Anti-ds DNA Tests To Diagnose CVD & SLE

  • ANCA Blog Banner


• Used in the diagnosis and management of Collagen Vascular Disease

• ANCA by IFA is highly sensitive

• c-ANCA (PR3) is increased in

  • Systemic Necrotizing Vasculitis
  • Wegener’s Granulomatosis
  • Churg Strauss Syndrome

C-ANCA Pattern

• p-ANCA (MPO) is increased in

  • Connective Tissue Disease
  • Inflammatory Bowel Disease
  • Autoimmune Liver Disease

P-ANCA Pattern

Anti-ds DNA


• Essential in the diagnosis of SLE. It is also detected in patients with other autoimmune diseases

• Anti-dsDNA is significant for the prognosis of SLE & monitoring the disease activity

• Sensitivity in patients with SLE is 70%

• Specificity in patients with autoimmune diseases is 99%


Central Processing Lab
Aston, 2nd Floor, Sundervan Complex, Opp. Union Bank, Above Mercedes Showroom, Andheri West, Mumbai – 400053

Book your appointment to diagnose Collagen Vascular Disease & CLE at Suburban Diagnostics.

Did you find this information useful :

1 Star2 Stars3 Stars4 Stars5 Stars (No Ratings Yet)