Suburban Diagnostics has partnered with Perkin Elmer to offer a comprehensive maternal screening program. Perkin Elmer is a known world leader in maternal-fetal health. The collaboration with Perkin Elmer is part of our endeavour to bring world-class quality to you and to your patients.
Screening Strategy | Time to test (in wks) |
Markers Used | Ultrasound Markers | Detection Rate (%) |
---|---|---|---|---|
FIRST TRIMESTER SCREENING | ||||
Dual Marker Test (Combined First Trimester Screening) |
11 – 13.6 | MA + BhCG, PAPP-A +NT |
CRL 45 – 84 mm |
~90 – 91 |
Pre-eclampsia Screening | 11 – 13.6 | PIGF, PAPP-A, BhCG, uAD & MAP |
CRL 45 – 84 mm |
~93 |
SECOND TRIMESTER SCREENING | ||||
Triple Marker Test | 15 – 21.6 | MA + AFP, BhCG, uE3 |
BPD 31 – 52 mm |
~65 – 70 |
Quadruple Marker Test | 15 – 21.6 | MA + AFP, BhCG, uE3, Inhibin – A |
BPD 31 – 52 mm |
~70 – 75 |
FIRST AND SECOND TRIMESTER SCREENING |
||||
Sequential Test OR Integrated Test |
11 – 13.6 | MA + BhCG, PAPP-A + NT |
CRL 45 – 84 mm |
~90 – 94 |
15 – 21.6 | MA + AFP, BhCG, uE3, Inhibin – A |
BPD 31 – 52 mm |
MA = Maternal Age
PAPP-A = Pregnancy Associated Plasma Protein – A
PIGF = Placental Growth Factor
βhCG = Free βHuman Chorionic Gonadotropin
AFP = Alpha Fetoprotein
NT = Nuchal Translucency
uE3 = Unconjugated Estriol
Easy graphical interpretation of reports with the use of life cycle software.
MoMs facilitate better accuracy and interpretation of the maternal screen results
Features | Prisca | Apha | Ssdw6 | LifeCycle TM |
---|---|---|---|---|
Flexible workflow including multiple risk strategies (i.e. combined, contingent, 1T Quard) | ✔ | ✔ | ||
Inclusion of NIPT in a continget workflow | No | ✔ | ||
Configurable risk paramters (i.e. median equations, correction factors) | Yes but not sure how flexible | ✔ | ✔ | |
Inclusion of PIGFin 1 T screening strategies | No | ✔ | ✔ | |
Flexible risk engine to incorporate new algorithms as needed | No | ✔ | ||
Updating capabilities for median equations | ✔ | ✔ | ✔ | |
Browser-based platform allowing multi-client access without software installation | No | ✔ | ✔ | |
Dashboard to monitor and review screening performance | No | ✔ | ✔ | ✔ |
Pre-eclampsia screening capabilities | No | ✔ | ✔ | ✔ |
Interfacing capabilitites to LIMS and ultrasound systems | LIMS | ✔ | ✔ |
With Perkin Elmer, we offer karyotyping on the latest BACs on beads technology. Bacterial artificial chromosomes-on-beads (BoBs™) assay technology has been introduced for the detection of common aneuploidies as well as specific microdeletion syndromes. It is the latest high throughput, cost-effective technology for rapid detection of fetal microdeletions and aneuploidies.